In this origin story, pygmy sloth, Romeo Fortez, is born on remote Escudo Island. At his naming ceremony, a once-in-a-millennium event imbibes him with powers of speed, intelligence, and irresistibly hypnotic good looks. When Romeo moves to New York he discovers that Professor Ian Weird-Warp, a geneticist obsessed with splicing animal genes together, has unleashed a gigantic mutant shar-wolf on the city.

With the help of some new human and animal friends, Romeo forms a team of crime fighters to save the city from the evil Professor Weird-Warp and his mutant creation.